Chemical Engineering

CHAP E4120 STATISTICAL MECHANICS AND COMP METHODS. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E3210) or equivalent thermodynamics course, or instructor's permission.
Boltzmann’s entropy hypothesis and its restatement to calculate the Helmholtz and Gibbs free energies and the grand potential. Applications to interfaces, liquid crystal displays, polymeric materials, crystalline solids, heat capacity and electrical conductivity of crystalline materials, fuel cell solid electrolytes, rubbers, surfactants, molecular self assembly, ferroelectricity. Computational methods for molecular systems. Monte Carlo (MC) and molecular dynamics (MD) simulation methods. MC method applied to liquid-gas and ferromagnetic phase transitions. Deterministic MD simulations of isolated gases and liquids. Stochastic MD simulation methods

CHBM E4321 The genome and the cell. 3 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: (BIOL UN2005) and (MATH UN2030)

The utility of genomic information lies in its capacity to predict the behavior of living cells in physiological, developmental, and pathological situations. The effect of variations in genome structure between individuals within a species, including those deemed healthy or diseased, and among species, can be inferred statistically by comparisons of sequences with behaviors, and mechanistically, by studying the action of molecules whose structure is encoded within the genome. This course examines known mechanisms that elucidate the combined effect of environmental stimulation and genetic makeup on the behavior of cells in homeostasis, disease states, and during development, and includes assessments of the probable effect of these behaviors on the whole organism.  Quantitative models of gene translation and intracellular signal transduction will be used to illustrate switching of intracellular processes, transient and permanent gene activation, and cell commitment, development, and death.

CHEE E4140 ENGINEERING SEPARATIONS. 3.00 points.

Design and analysis of unit operations employed in chemical engineering separations. Fundamental aspects of single and multistaged operations using both equilibrium and rate-based methods. Examples include distillation, absorption and stripping, extraction, membranes, crystallization, bioseparations, and environmental applications

CHEE E4252 INTRO-SURFACE AND COLLOID SCI. 3.00 points.

Lect: 3.

Prerequisites: elementary physical chemistry.
The principles of surfaces and colloid chemistry critical to range of technologies indispensable to modern life. Surface and colloid chemistry has significance to life sciences, pharmaceuticals, agriculture, environmental remediation and waste management, earth resources recovery, electronics, advanced materials, enhanced oil recovery, and emerging extraterrestrial mining. Topics include: thermodynamics of surfaces, properties of surfactant solutions and surface films, electrokinetic phenomena at interfaces, principles of adsorption and mass transfer and modern experimental techniques. Leads to deeper understanding of interfacial engineering, particulate dispersions, emulsions, foams, aerosols, polymers in solution, and soft matter topics

CHEE E4530 CORROSION OF METALS. 3.00 points.

Lect: 3.

Prerequisites: (CHEE E3010) or CHEE E3010 or equivalent
The theory of electrochemical corrosion, corrosion tendency, rates, and passivity. Application to various environments. Cathodic protection and coatings. Corrosion testing

CHEE E6201 Topics in Electrochemical Energy Storage and Conversion. 3.00 points.

CHEE E6252 ADV SURFACE/COLLOID CHEMISTRY. 3.00 points.

Lect:2. Lab:3.

Prerequisites: (CHEE E4252) CHEE E4252.
Applications of surface chemistry principles to wetting, flocculation, flotation, separation techniques, catalysis, mass transfer, emulsions, foams, aerosols, membranes, biological surfactant systems, microbial surfaces, enhanced oil recovery, and pollution problems. Appropriate individual experiments and projects. Lab required

CHEN E Fieldwork. 0 points.

Not offered during 2023-2024 academic year.

CHEN E1000 Chemical Engineering for Humanity. 1.00 point.

Introduction to the role of Chemical Engineering in addressing grand challenges facing humanity. Address challenges illustrating the important role that Chemical Engineers play in solving societal problems, including to those related to climate change, biotechnology and medicine, clean energy, and sustainable manufacturing of chemicals and materials

CHEN E2100 Material and Energy Balances. 3.00 points.

Lect: 2.5

Prerequisites: First-year chemistry and physics or equivalent.
Serves as an introduction to the chemical engineering profession. Students are exposed to concepts used in the analysis of chemical engineering problems. Rigorous analysis of material and energy balances on open and closed systems is emphasized. An introduction to important processes in the chemical and biochemical industries is provided

CHEN E3020 ANALYSIS OF CHEM ENGIN PROBLMS. 3.00 points.

Lect: 1 Lab: 1

Prerequisites: vector calculus, ordinary differential equations.
Corequisites: CHEE E3010
Advance chemical-engineering problem-solving skills through the use of computational tools (primarily developed in Excel or Python). Examples are drawn from thermodynamics, transport phenomena, and chemical kinetics. The course is project based, emphasizing data analysis and report writing. Unstructured collaboration with peers is highly encouraged. Requisite numerical methods and Chemical Engineering concepts introduced

CHEN E3110 PRINCIPLES OF TRANSPORT PHENOMENA. 3.00 points.

Lect: 3.

Prerequisites: mechanics, vector calculus, ordinary differential equations.
Corequisites: CHEN E3020
A mechanistic and mathematical description of the engineering fundamentals of heat and mass transport and fluid mechanics based on mass, momentum and energy balances from the molecular to the continuum to the industrial device scale. Problems and applications will focus on energy, biological and chemical systems and processes

CHEN E3120 TRANSPORT PHENOMENA II. 3.00 points.

Lec: 3.

Prerequisites: (CHEN E3110) CHEN E3110x
Corequisites: CHEN E3220
Developments in Transport I are extended to handle turbulence. Topics include: Turbulent energy cascade, wall-bounded turbulent shear flow, time-averaging of the equations of change, Prandtls mixing length hypothesis for the Reynolds stress, the Reynolds analogy, continuum modeling of turbulent flows and heat transfer processes, friction factor, and Nusselt number correlations for turbulent conditions. Then macroscopic (system-level) mass, momentum, and energy balances for one-component systems are developed and applied to complex flows and heat exchange processes. The final part focuses on mass transport in mixtures of simple fluids: Molecular-level origins of diffusion phenomena, Ficks law and its multicomponent generalizations, continuum-level framework for mixtures and its application to diffusion dominated processes, diffusion with chemical reaction, and forced/free convection mass transport

CHEN E3210 CHEM ENGINEERNG THERMODYNAMICS. 3.00 points.

Lect: 3.

Prerequisites: (CHEE E3010) and (CHEN E2100) CHEE E3010 and CHEN E3100.
Corequisites: CHEN E3220.
This course deals with fundamental and applied thermodynamic principles that form the basis of chemical engineering practice. Topics include phase equilibria, methods to treat ideal and non-ideal mixtures, and estimation of properties

CHEN E3230 REACTOR KINETICS/REACTOR DESIGN. 3.00 points.

Reaction kinetics, applications to the design of batch and continuous reactors. Multiple reactions, non-isothermal reactors. Analysis and modeling of reactor behavior

CHEN E3810 CHEM ENG ＆ APPLIED CHEM LAB. 3.00 points.

Lab: 3.

Prerequisites: (CHEN E3110) and (CHEN E3120) and (CHEN E4230) and (CHEN E2100) and (CHEE E3010) and (CHEN E3210) and (CHEN E4140) and (CHEN E4500) or Completion of core chemical engineering curricula through the fall semester of senior year (includes: CHEN E3110, E3120, E4230, E3100, E3010, E3210, E4140, E4500), OR instructor's permission.
Emphasizes active, experiment-based resolution of open-ended problems involving use, design, and optimization of equipment, products, or materials. Under faculty guidance students formulate, carry out, validate, and refine experimental procedures, and present results in oral and written form. Develops analytical, communications, and cooperative problem-solving skills in the context of problems that span from traditional, large scale separations and processing operations to molecular level design of materials or products. Sample projects include: scale up of apparatus, process control, chemical separations, microfluidics, surface engineering, molecular sensing, and alternative energy sources. Safety awareness is integrated

CHEN E3899 Research Training. 0.00 points.

Research training course. Recommended in preparation for laboratory related research

CHEN E3900 UNDERGRADUATE RESEARCH PROJECT. 0.00-6.00 points.

Candidates for the B.S. degree may conduct an investigation of some problem in chemical engineering or applied chemistry or carry out a special project under the supervision of the staff. Credit for the course is contingent upon the submission of an acceptable thesis or final report. No more than 6 points in this course may be counted toward the satisfaction of the B.S. degree requirements

CHEN E3999 UNDERGRADUATE FIELDWORK. 1.00-2.00 points.

Prerequisites: Restricted to Chemical Engineering undergraduate students.
Provides work experience on chemical engineering in relevant intern or fieldwork experience as part of their program of study as determined by the instructor. Written application must be made prior to registration outlining proposed internship/study program. A written report describing the experience and how it relates to the chemical engineering core curriculum is required. Employer feedback on student performance and the quality of the report are the basis of the grade. This course may not be taken for pass/fail or audited. May not be used as a technical or non­technical elective. May be repeated for credit, but no more than 3 points total of CHEN E3999 may be used for degree credit

CHEN E4001 ESSENTIALS OF CHEM ENGIN A. 3.00 points.

Lect: 3

Prerequisites: First-year chemistry and physics, vector calculus, ordinary differential equations, and the instructor's permission.
Part of an accelerated consideration of the essential chemical engineering principles from the undergraduate program, including selected topics from Introduction to Chemical Engineering, Transport Phenomena I and II, and Chemical Engineering Control. While required for all M.S. students with Scientist to Engineer status, the credits from this course may not be applied toward any chemical engineering degree

CHEN E4002 ESSENTIALS OF CHEM ENGIN B. 3.00 points.

Lect: 3.

Prerequisites: First-year chemistry and physics, vector calculus, ordinary differential equations, and the instructor's permission.
Part of an accelerated consideration of the essential chemical engineering principles from the undergraduate program, including topics from Reaction Kinetics and Reactor Design, Chemical Engineering Thermodynamics, I and II, and Chemical and Biochemical Separations. While required for all M.S. students with Scientist to Engineer status, the credits from this course may not be applied toward any chemical engineering degree

CHEN E4010 MATH METHODS IN CHEMICAL ENGIN. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E3120) and (CHEN E4230) or equivalent, or instructor's permission.
Mathematical description of chemical engineering problems and the application of selected methods for their solution. General modeling principles, including model hierarchies. Linear and nonlinear ordinary differential equations and their systems, including those with variable coefficients. Partial differential equations in Cartesian and curvilinear coordinates for the solution of chemical engineering problems

CHEN E4020 PROTECTN OF INDUST/INTELL PROP. 3.00 points.

Lect: 3.

To expose engineers, scientists and technology managers to areas of the law they are most likely to be in contact with during their career. Principles are illustrated with various case studies together with active student participation

CHEN E4110 MECHANISMS OF TRANSPORT. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E3120) CHEN E3110X and CHEN E3120Y or the equivalent
Continuum frame-work for modeling non-equilibrium phenomena in fluids with clear connections to the molecular/microscopic mechanisms for conductive transport. Continuum balances of mass and momentum; continuum-level development of conductive momentum flux (stress tensor) for simple fluids; applications of continuum framework for simple fluids (lubrication flows, creeping flows). Microscopic developments of the stress for simple and/or complex fluids; kinetic theory and/or liquid state models for transport coefficients in simple fluids; Langevin/Fokker- Plank/Smoluchowski framework for the stress in complex fluids; stress in active matter; applications for complex fluids

CHEN E4112 TRANSPORT IN FLUID MIXTURES. 3.00 points.

Prerequisites: CHEN E3110X and CHEN E3120Y or the equivalent
Develops and applies non-equilibrium thermodynamics for modeling of transport phenomena in fluids and their mixtures. Continuum balances of mass, energy and momentum for pure fluids; non-equilibrium thermodynamic development of Newtons law of viscosity and Fouriers law; applications (conduction dominated energy transport, forced and free convection energy transport in fluids); balance laws for fluid mixtures; non-equilibrium thermodynamic development of Ficks law; applications (diffusion-reaction problems, analogy between energy and mass transport processes, transport in electrolyte solutions, sedimentation)

CHEN E4115 Topics in Transport Phenomena. 3 points.

Prerequisites: Undergraduate fluid mechanics, or transport phenomena, or instructor's permission.

Self-contained treatments of selected topics in transport phenomena (e.g., rheology, nonequilibrium thermodynamics, molecular-level aspects of transport turbulence). Topics and instructor may change from year to year. Intended for junior/senior level undergraduates and graduate students in engineering and the physical sciences.

CHEN E4130 ADV CHEM ENGI THERMODYNAMICS. 3.00 points.

Prerequisites: Successful completion of an undergraduate chemical engineering thermodynamics course.
The course provides a rigorous and advanced foundation in chemical engineering thermodynamics suitable for chemical engineering PhD students expected to undertake diverse research projects. Topics include Intermolecular interactions, non-ideal systems, mixtures, phase equilibria and phase transitions and interfacial thermodynamics

CHEN E4140 ENGINEERING SEPARATIONS. 3.00 points.

Prerequisites: (CHEN E2100) and (CHEN E3120) and (CHEN E3210) or instructor's permission.
Design and analysis of unit operations employed in chemical engineering separations. Fundamental aspects of single and multistaged operations using both equilibrium and rate-based methods. Examples include distillation, absorption and stripping, extraction, membranes, crystallization, bioseparations, and environmental applications

CHEN E4150 COMPUTATIONAL FLUID DYNAMICS I. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: Undergraduate Fluid Mechanics

CHEN E4180 Machine Learning for Biomolecular and Cellular Applications. 3.00 points.

Introduction to machine learning techniques with applications to biological systems, emphasizing cell-biological molecular mechanisms and applications, and computational simulation. Overview of biology. Introduction to biological neurons and neural networks, learning and memory. Parallels between biological and artificial neural networks. Deep neural networks are introduced, hands-on computational experience for students. Big data from experiments or computational simulations: machine learning to extract mechanisms, dimensional reduction. Deep learning applications include drug discovery, protein structure prediction, molecular coarse-graining for simulations, and acceleration of molecular dynamics simulations

CHEN E4201 ENGIN APPL OF ELECTROCHEMISTRY. 3.00 points.

Lect: 3.

Prerequisites: Physical chemistry and a course in transport phenomena.
Engineering analysis of electrochemical systems, including electrode kinetics, transport phenomena, mathematical modeling, and thermodynamics. Common experimental methods are discussed. Examples from common applications in energy conversion and metallization are presented

CHEN E4230 REACTOR KINETICS/REACTOR DESGN. 3.00 points.

Reaction kinetics, applications to the design of batch and continuous reactors. Multiple reactions, non-isothermal reactors. Analysis and modeling of reactor behavior

CHEN E4231 SOLAR FUELS. 3.00 points.

Prerequisites: (CHEN E4230) or Graduate standing or CHEN E4230.
Fundamentals and applications of solar energy conversion, especially technologies for conversion of sunlight into storable chemical energy or solar fuels. Topics include fundamentals of photoelectrochemistry, kinetics of solar fuels production, solar harvesting technologies, solar reactors, and solar thermal production of solar fuels. Applications include solar fuels technology for grid-scale energy storage, chemical industry, manufacturing, environmental remediation

CHEN E4235 SURFACE REACTIONS ＆ KINETICS. 3.00 points.

CHEN E4300 CHEM PROC. CONTROL ＆ SAFETY. 3.00 points.

Lab: 2.

Prerequisites: Material and energy balances.
Ordinary differential equations including Laplace transforms. Reactor Design. An introduction to process control applied to chemical engineering through lecture and laboratory. Concepts include the dynamic behavior of chemical engineering systems, feedback control, controller tuning, and process stability

CHEN E4320 MOLECULAR PHENOMENA-CHEM ENGI. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: (CHEN E3120) or instructor's permission.
This course introduces a molecular level understanding of topics in modern chemical engineering. It builds upon and validates the concepts presented in the rest of the chemical engineering curriculum via a molecular perspective

CHEN E4325 BIOSEPARATIONS. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: (CHEN E2100 and CHEE E3010 and CHEN E3110 and CHEN E3230) or equivalent.

The course focuses on design and analysis of the concentration, recovery, and isolation of biological molecules relevant in biotechnology. The unit operations used in recovery and purification of biological molecules will be presented in this course. Theory and design of filtration, microfiltration, centrifugation, cell disruption, extraction, adsorption, chromatography, precipitation, ultrafiltration, crystallization, and drying will be discussed. By the end of the course students will have an understanding of basic principles of downstream processing, design and operations of various unit operations used in recovery of biological products, examining traditional unit operations, as well as new concepts and emerging technologies that are likely to benefit biochemical product recovery in the future.

CHEN E4330 ADVANCED CHEMICAL KINETICS. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E4230) or instructor's permission.
Complex reactive systems. Catalysis. Heterogeneous systems, with an emphasis on coupled chemical kinetics and transport phenomena. Reactions at interfaces (surfaces, aerosols, bubbles). Reactions in solution

CHEN E4380 Green Chemical Engineering ＆ Innovation. 3.00 points.

Approaches used in chemistry and chemical engineering to design green, sustainable products and processes; focus of using the tenets of green chemistry as a means for chemical innovation. Technical and design practice and measuring the impacts of green and conventional approaches emphasized. Themes of business, regulatory, ethical, and social considerations relevant to chemical engineering practice

CHEN E4400 CHEMICAL PROCESS DEVELOPMENT. 3.00 points.

Lect: 3.

Prerequisites: (CHEM UN3443) or equivalent, or instructor's permission.
Chemical engineering fundamentals as applied to process research, development, and manufacturing of pharmaceutical products. Course topics include: comprehensive overview of the biopharmaceutical business (therapeutic areas, markets, drug discovery, clinical development, commercialization), process research, creation, development, optimization, sustainability, green chemistry and engineering, safety (patient, process, and personnel), unit operations and associated calculations relevant to pharmaceutical processes, process scale-up, implementation, assessment, technology transfer, new technologies, economic analysis, drug product formulation and manufacturing, and regulatory considerations. Case studies and real-life examples are presented throughout the course

CHEN E4444 Climate Technology. 3.00 points.

Scientific and economic analysis of real-world technologies for climate change mitigation and adaptation. Partner with students from the business school to assess and assigned technology based on technical viability, commercial opportunity, and impact on mitigating or adapting to climate change. Assigned technologies provided by the investment community to teams of four, with expectations for independent research on the technologies, with deliverables of written and oral presentations

CHEN E4500 PROCESS ＆ PRODUCT DESIGN I. 4.00 points.

Lect: 4.

Prerequisites: (CHEN E2100) and (CHEN E4140) CHEN E2100, CHEN E4140.
The practical application of chemical engineering principles for the design and economic evaluation of chemical processes and plants. Use of ASPEN Plus for complex material and energy balances of real processes. Students are expected to build on previous coursework to identify creative solutions to two design projects of increasing complexity. Each design project culminates in an oral presentation, and in the case of the second project, a written report

CHEN E4501 PROCESS SAFETY. 3.00 points.

Aimed at seniors and graduate students. Provides classroom experience on chemical engineering process safety as well as Safety in Chemical Engineering certification. Process safety and process control emphasized. Application of basic chemical engineering concepts to chemical reactivity hazards, industrial hygiene, risk assessment, inherently safer design, hazard operability analysis, and engineering ethics. Application of safety to full spectrum of chemical engineering operations

CHEN E4510 PROCESS ＆ PRODUCT DESIGN II. 4.00 points.

Lect: 4.

Prerequisites: (CHEN E4500)
Students carry out a semesterlong process or product design course. The project culminates with a formal written design report and a public presentation. Recitation section required

CHEN E4550 Climate Engineering. 3.00 points.

Critical analysis of proposed approaches for climate mitigation involving intentional modification of the environment (also known as climate engineering, or geoengineering), with a focus on solar radiation management and weather modification. Emphasis on technical basis, potential intentional and unintentional environmental impacts, cost-benefit analysis, and design considerations. History, ethics, social dimensions, and governance of climate engineering and climate engineering research

CHEN E4580 ARTIFICIAL INTELLIGENCE IN CHEMICAL ENGINEERING. 3.00 points.

CHEN E4600 AEROSOLS. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E3120) or CHEN E3120 or instructor's permission.
Aerosol impacts on indoor and outdoor air quality, health, and climate. Major topics include aerosol sources, physics, and chemistry; field and laboratory techniques for aerosol characterization; aerosol direct and indirect effects on climate; aerosols in biogeochemical cycles and climate engineering; health impacts including exposure to ambient aerosols and transmission of respiratory disease

CHEN E4610 CHEMICAL PRODUCT DESIGN. 3.00 points.

Lect: 3.

Prerequisites: (CHEN E3210) and (CHEM UN3443) or equivalent, or instructor's permission.
Application of chemical and engineering knowledge to the design of new chemical products. Relationships between composition and physical properties. Strategies for achieving desired volumetric, rheological, phase equilibrium, thermal, and environmental behavior. Case studies, such as separation solvents, blood substitutes, refrigerants, and aircraft deicing fluids

CHEN E4620 INTRO-POLYMERS/SOFT MATERIALS. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: An elementary course in physical chemistry or thermodynamics. Organic chemistry, statistics, calculus and mechanics are helpful, but not essential.

An introduction to the chemistry and physics of soft material systems (polymers, colloids, organized surfactant systems and others), emphasizing the connection between microscopic structure and macroscopic physical properties. To develop an understanding of each system, illustrative experimental studies are discussed along with basic theoretical treatments. High molecular weight organic polymers are discussed first (basic notions, synthesis, properties of single polymer molecules, polymer solution and blend thermodynamics, rubber and gels). Colloidal systems are treated next (dominant forces in colloidal systems, flocculation, preparation and manipulation of colloidal systems) followed by a discussion of self-organizing surfactant systems (architecture of surfactants, miceles and surfactant membranes, phase behavior).

CHEN E4630 TOPICS IN SOFT MATERIALS. 3.00 points.

Prerequisites: Physical chemistry or instructor's permission.
Self-contained treatments of selected topics in soft materials (e.g. polymers, colloids, amphiphiles, liquid crystals, glasses, powders). Topics and instructor may change from year to year. Intended for junior/senior level undergraduates and graduate students in engineering and the physical sciences

CHEN E4650 POLYMER PHYSICS. 3.00 points.

Prerequisites: (CHEN E3110) and (CHEN E3120) and (CHEN E4620) CHEE E3110, CHEN E3120 and E4620.
Senior undergraduate/first-year graduate course on the physics of polymer systems. Topics include scaling behavior of chains under different conditions, mixing thermodynamics, networks and geation, polymer dynamics, including retation and entanglements. Special topics: nanocomposites

CHEN E4660 BIOCHEMICAL ENGINEERING. 3.00 points.

Lect: 3

Prerequisites: (CHEN E4320) or CHEN E4320 or instructor's permission.
Engineering of biochemical and microbiological reaction systems. Kinetics, reactor analysis, and design of batch and continuous fermentation and enzyme processes. Recovery and separations in biochemical engineering systems

CHEN E4670 CHEMICAL ENGINEERING DATA ANALYSIS. 3.00 points.

Course is aimed at senior undergraduate and graduate students. Introduces fundamental concepts of Bayesian data analysis as applied to chemical engineering problems. Covers basic elements of probability theory, parameter estimation, model selection, and experimental design. Advanced topics such as nonparametric estimation and Markov chain Monte Carlo (MEME) techniques are introduced. Example problems and case studies drawn from chemical engineering practice are used to highlight the practical relevance of the material. Theory reduced to practice through programming in Mathematica. Course grade based on midterm and final exams, biweekly homework assignments, and final team project

CHEN E4690 Managing. 3 points.

Prerequisites: CHEN E4300 or equivalent, or instructor's permission.

Fundamental concepts and tools of process systems engineering for modeling, analyzing, and managing enterprisewide risk in complex systems. Case studies present important systemic failures in different domains and their lessons. Develop and analyze risk models for real-life-inspired case studies.

CHEN E4700 PRINCIPLES OF GENOMIC TECHNOL. 3.00 points.

Lect: 3.

Prerequisites: Undergraduate-level biology, organic chemistry and instructor's permission.
Chemical and physical aspects of genome structure and organization, genetic information flow from DNA to RNA to Protein. Nucleic acid hybridization and sequence complexity of DNA and RNA. Genome mapping and sequencing methods. The engineering of DNA polymerase for DNA sequencing and polymerase chain reaction. Fluorescent DNA sequencing and high-throughput DNA sequencer development. Construction of gene chip and micro array for gene expression analysis. Technology and biochemical approach for functional genomics analysis. Gene discovery and genetics database search method. The application of genetic database for new therapeutics discovery

CHEN E4740 BIOL TRANSPORT-RATE PHENOMENA. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: (CHEN E3110) or (BIOL UN2005) or (CHEN E3210) or (BMCH E3500) Any two of the prerequisite courses
Analysis of transport and rate phenomena in biological systems and in the design of biomimetic transport-reaction systems for technological and therapeutic applications. Modeling of homogeneous and heterogeneous biochemical reactions. The Bases of biological transport: roles of convection, ordinary diffusion, forced diffusion. Systems where reaction and transport interact strongly. Applications to natural and artificial tissue beds, tumor modeling, controlled release, natural and artificial organ function

CHEN E4780 QUANT METHODS IN CELL BIOLOGY. 3.00 points.

Lect: 3.

Prerequisites: Elementary calculus, physics and biology, or instructor's permission.

Quantitative statistical analysis and mathematical modeling in cell biology for an audience with diverse backgrounds. The course presents quantitative methods needed to analyze complex cell biological experimental data and to interpret the analysis in terms of the underlying cellular mechanisms. Optical and electrical experimental methods to study cells and basic image analysis techniques are described. Methods of statistical analysis of experimental data and techniques to test and compare mathematical models against measured statistical properties will be introduced.  Concepts and techniques of mathematical modeling will be illustrated by applications to mechanosensing in cells, the mechanics of cytokinesis during cell division and synaptic transmission in the nervous system. Image analysis, statistical analysis, and model assessment will be illustrated for these systems.

CHEN E4800 Protein engineering. 3 points.

Lect: 3.

Prerequisites: (CHEN E4230) or CHEN E4230, may be taken concurrently or the instructors permission.

Fundamental tools and techniques currently used to engineer protein molecules.  Methods used to analyze the impact of these alterations on different protein functions with specific emphasis on enzymatic catalysis.  Case studies reinforce concepts covered, and demonstrate the wide impact of protein engineering research.  Application of basic concepts in the chemical engineering curriculum (reaction kinetics, mathematical modeling, thermodynamics) to specific approaches utilized in protein engineering.

CHEN E4850 CONTAMINATED SITE CLEAN UP. 3.00 points.

Not offered during 2023-2024 academic year.

The course is aimed at senior undergraduate and graduate students. It introduces the science fundamentals and the regulations that govern the cleanup of sites contaminated with hazardous materials and discusses the processes used for their treatment and safe disposal. Covers the methods used to investigate the extent of contamination in soil, groundwater, and sediment. Uses case studies to illustrate the application of technologies used to address different categories of contaminants (metals, volatile and semi-volatile organic). Applies basic concepts in the chemical engineering curriculum to specific approaches utilized in characterizing the fate and transport of contaminants and for designing the engineering processes utilized in their treatment

CHEN E4860 NMR BIOSOFTENG. 3.00 points.

Prerequisites: Prerequisites: Physics UN1401, Principles of Chem. Eng. Thermodynamics CHEE E3010, or instructor's approval
This course is for junior/senior undergraduates and graduate (MS) students. The course focuses on the fundamentals of nuclear magnetic resonance (NMR) spectroscopy and imaging in fields ranging from biomedical engineering to electrochemical energy storage. Course material covers basic NMR theory, instrumentation (including in situ/operando setup), data interpretation, and experimental design to couple with other materials characterization strategies. Course grade based on problem sets, quizzes, and final project presentation

CHEN E4870 Synthetic Organogenesis. 3.00 points.

Prerequisites: Any quantitative undergraduate course with elements of biology, such as Chemistry, Biochemical Engineering/Biochemistry, Biophysics, but also at the instructor’s permission.

Prerequisites: see notes re: points
The goal of synthetic organogenesis is to use stem cells to reconstitute aspects of embryo development and organ formation in vitro. Examines the molecular basis of human embryogenesis. Introduces synthetic organogenesis as an interdisciplinary field. Students learn to recognize generic molecular mechanisms behind signaling and cell lineage specification. Covers recent advances in applying engineering and contemporary biology to creating organoids and organs on chips using human stem cells

CHEN E4880 ATOMISTIC SIMULATIONS FOR SCIENCE AND EN. 3.00 points.

Many materials properties and chemical processes are governed by atomic-scale phenomena such as phase transformations, atomic/ionic transport, and chemical reactions. Thanks to progress in computer technology and methodological development, now there exist atomistic simulation approaches for the realistic modeling and quantitative prediction of such properties. Atomistic simulations are therefore becoming increasingly important as a complement for experimental characterization, to provide parameters for meso- and macroscale models, and for the in-silico discovery of entirely new materials. This course aims at providing a comprehensive overview of cutting-edge atomistic modeling techniques that are frequently used both in academic and industrial research and engineering. Participants will develop the ability to interpret results from atomistic simulations and to judge whether a problem can be reliably addressed with simulations. The students will also obtain basic working knowledge in standard simulation software

CHEN E4890 BIOPHARMACEUTICALS PRODUCT DEV. 3.00 points.

Aimed at graduate students of Chemical Engineering. Examines the application of Chemical Engineering fundamentals and entrepreneurship in starting up a biopharmaceutical company and in developing a biopharmaceutical product. Serves as a description of the major stages of developing a biopharmaceutical product. Topics presented will include drug discovery, preclinical and clinical development, IP, manufacturing, and regulatory process. In addition, implementation of the lean startup methodology, business valuation, and financial considerations for a biopharmaceutical startup will be offered. Basic topics in the chemical engineering curriculum (reaction kinetics, mathematical modeling, unit operations, thermodynamics), as well as specific topics in developing biopharmaceuticals will be discussed in this course

CHEN E4899 Research Training. 0.00 points.

Research training course. Recommended in preparation for laboratory related research

CHEN E4900 TOPICS IN CHEMICAL ENGINEERING. 3.00 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: Instructor's permission

Additional current topics in chemical engineering taught by regular or visiting faculty. Special topics arranged as the need and availability arise. Topics usually offered on a one-time basis. Since the content of this course changes each time it is offered, it may be repeated for credit.

CHEN E4910 SOLID STATE CHEMISTRY IN PHARMACEUTICAL. 3.00 points.

Prerequisites: Pre-requisites: Thermodynamics (any), or General Chemistry Students must be engineering juniors or seniors, engineering graduate students, or PhD and undergraduate students in the sciences, e.g. chemistry or biology

CHEN E4920 PHARMACEUTICAL INDUSTRY FOR ENGINEERS. 3.00 points.

Pre-requisites: General Chemistry, Organic Chemistry

This course provides students an overview of biopharmaceutical design, development, manufacturing, and regulatory requirements from an engineering perspective. The unit operations, equipment selection, and process development associated with small molecule, biologics, and vaccine manufacturing are all illustrated through examples, and quantitative engineering approaches are applied as appropriate. Small molecules, biologics, vaccines, solid oral formulations, sterile processing, and design of experiments (DoE) are treated along with a module on regulatory requirements

CHEN E4930 Biopharmaceutical Process Laboratory. 3.00 points.

Prerequisites: Organic Chemistry Lab I, Undergraduate Organic Chemistry.

Prerequisites: see notes re: points
Intended for junior and senior undergraduate and graduate students interested in gaining hands-on experience in biopharmaceutical processing. Processes and unit operations applied widely in the biopharmaceutical industry, including tableting, dissolution, disintegration, fermentation, chromatography, tangential flow filtration, mixing, and crystallization. Process parameters, chemical and molecular properties, process performance, and product attributes. Includes a combination of lectures (given during lab time), experiments, and report writing

CHEN E4999 FIELDWORK. 1.00-3.00 points.

CHEN E6543 CHEMICAL ENGIN RES METHODOLOGY. 1.00 point.

CHEN E6630 Special topics in soft condensed matter. 3 points.

Lect: 3.Not offered during 2023-2024 academic year.

Tutorial lectures on selected  topics in soft condensed matter.

CHEN E6910 Theoretical methods in polymer physics. 3 points.

Lect: 3.Not offered during 2023-2024 academic year.

Prerequisites: CHAP 4120 or equivalent statistical mechanics course, or the instructor's permission.

Modern methods for understanding polymeric liquids and critical phenomena are introduced and applied in detail. Scaling and universality. Relationship of high polymer physics to critical phenomena. Landau theory, self-consistent field method. Scaling approach. Renormalization group theory. Epsilon expansion for polymer and other critical exponents. Applications to polymer statics and dynamics, and to other complex fluids.

CHEN E8001 M.S. Chemical Engineering Colloquium. 0 points.

Required for all M.S. students in residence in their first semester. Topics related to professional development and the practice of chemical engineering are discussed. No degree credit is granted. This course is not intended for M.S./ Ph.D. students or doctoral students.

CHEN E8100 TOPICS IN BIOLOGY. 3.00 points.

Lect: 3.

Prerequisites: The instructor's permission.
This research seminar introduces topics at the forefront of biological research in a format and language accessible to quantitative scientists and engineers lacking biological training. Conceptual and technical frameworks from both biological and physical science disciplines are utilized. The objective is to reveal to graduate students where potential lies to apply techniques from their own disciplines to address pertinent biological questions in their research. Classes entail reading, criticism and group discussion of research papers and textbook materials providing overviews to various biological areas including: evolution, immune system, development and cell specialization, the cytoskeleton and cell motility, DNA transcription in gene circuits, protein networks, recombinant DNA technology, aging, and gene therapy

CHEN E9000 CHEMICL ENGINEERING COLLOQUIUM. 0.00 points.

0 pts. Col: 1.

All graduate students are required to attend the department colloquium as long as they are in residence. No degree credit is granted

CHEN E9001 MASTER'S COLLOQUIUM. 0.00 points.

Required for all M.S. students in residence in their first semester. Topics related to professional development and the practice of chemical engineering. No degree credits granted. Intended for M.S./Ph.D. students or doctoral students

CHEN E9400 MASTERS RESEARCH. 1.00-6.00 points.

Prescribed for M.S. and Ch.E. candidates; elective for others with the approval of the Department. Degree candidates are required to conduct an investigation of some problem in chemical engineering or applied chemistry and to submit a thesis describing the results of their work. No more than 6 points in this course may be counted for graduate credit, and this credit is contingent upon the submission of an acceptable thesis. The concentration in pharmaceutical engineering requires a 2-point thesis internship

CHEN E9500 DOCTORAL RESEARCH. 1.00-15.00 points.

Prerequisites: The qualifying examinations for the doctorate. Open only to certified candidates for the Ph.D. and Eng.Sc.D. degrees.
Open only to certified candidates for the Ph.D. and Eng.Sc.D. degrees. Doctoral candidates in chemical engineering are required to make an original investigation of a problem in chemical engineering or applied chemistry, the results of which are presented in their dissertations. No more than 15 points of credit toward the degree may be granted when the dissertation is accepted by the department

CHEN E9800 Doctoral research instruction. 0 points.

3, 6, 9 or 12 pts.

A candidate for the Eng.Sc.D. degree in chemical engineering must register for 12 points of doctoral research instruction. Registration in CHEN E9800 may not be used to satisfy the minimum residence requirement for the degree.

CHEN E9900 Doctoral dissertation. 0 points.

0 pts.

Open only to certified doctoral candidates. A candidate for the doctorate in chemical engineering may be required to register for this course in every term after the student's course work has been completed, and until the dissertation has been accepted.

MECH E4320 INTRO TO COMBUSTION. 3.00 points.

Thermodynamics and kinetics of reacting flows; chemical kinetic mechanisms for fuel oxidation and pollutant formation; transport phenomena; conservation equations for reacting flows; laminar nonpremixed flames (including droplet vaporization and burning); laminar premixed flames; flame stabilization, quenching, ignition, extinction, and other limit phenomena; detonations; flame aerodynamics and turbulent flames