Biochemistry

Undergraduate Office: 340 Havemeyer; 212-854-2163

Departmental Office: 344 Havemeyer; 212-854-2202
http://www.columbia.edu/cu/chemistry/

Director of Undergraduate Studies: Prof. Karen Phillips, 422 Havemeyer; 212-851-7534; kep12@columbia.edu

Program Manager for Undergraduate Studies: Dr. Vesna Gasperov, 211A Havemeyer; 212-854-2017; vg2231@columbia.edu

Biochemistry Advisers:
Biology: Prof. Brent Stockwell, 1208 Northwest Corner Building; 212-854-2919; stockwell@biology.columbia.edu
 

Chemistry, the study of molecules, is a central science interesting for its own sake but also necessary as an intellectual link to the other sciences of biology, physics, and environmental science. Faculty find the various disciplines of chemistry fascinating because they establish intellectual bridges between the macroscopic or human-scale world that we see, smell, and touch, and the microscopic world that affects every aspect of our lives. The study of chemistry begins on the microscopic scale and extends to engage a variety of different macroscopic contexts.

Chemistry is currently making its largest impact on society at the nexus between chemistry and biology and the nexus between chemistry and engineering, particularly where new materials are being developed. A typical chemistry laboratory now has more computers than test tubes and no longer smells of rotten eggs.

The chemistry department majors are designed to help students focus on these new developments and to understand the factors influencing the nature of the discipline. Because the science is constantly changing, courses change as well, and while organic and physical chemistry remain the bedrock courses, they too differ greatly from the same courses 40 years ago. Many consider biochemistry to be a foundation course as well. Although different paths within the chemistry major take different trajectories, there is a core that provides the essential foundation students need regardless of the path they choose. Students should consider majoring in chemistry if they share or can develop a fascination with the explanatory power that comes with an advanced understanding of the nature and influence of the microscopic world of molecules.

Students who choose to major in chemistry may elect to continue graduate study in this field and obtain a Ph.D. which is a solid basis for a career in research, either in the industry or in a university. A major in chemistry also provides students with an astonishing range of career choices such as working in the chemical or pharmaceutical industries or in many other businesses where a technical background is highly desirable. Other options include becoming a financial analyst for a technical company, a science writer, a high school chemistry teacher, a patent attorney, an environmental consultant, or a hospital laboratory manager, among others. The choices are both numerous and various as well as intellectually exciting and personally fulfilling.

Advanced Placement

The department grants advanced placement (AP) credit for a score of 4 or 5. The amount of credit granted is based on the results of the department placement exam and completion of the requisite course. Students who are placed into CHEM UN1604 Intensive General Chemistry (Lecture) are granted 3 points of credit; students who are placed into CHEM UN2045 Intensive Organic Chemistry I (Lecture)-CHEM UN2046 Intensive Organic Chemistry II (Lecture) are granted 6 points of credit. In either case, credit is granted only upon completion of the course with a grade of C or better. Students must complete a department placement exam prior to registering for either of these courses.

Programs of Study

The Department of Chemistry offers four distinct academic major programs for undergraduates interested in professional-level training and education in the chemical sciences: chemistry, chemical physics, biochemistry and environmental chemistry. For students interested in a program of less extensive study and coursework, the department offers a concentration in chemistry.

Course Information

The results of the placement exam are used to advise students which track to pursue. The Department of Chemistry offers three different tracks. Students who wish to take Track 2 or 3 classes must take the placement exam. Students who wish to pursue Track 1 classes do not need to take the placement exam.

Track Information

In the first year, Track 1 students with one year of high school chemistry take a one-year course in general chemistry, and the one-term laboratory course that accompanies it. In the second year, students study organic chemistry, and take organic chemistry laboratory.

Students who qualify by prior examination during orientation week can place into the advanced tracks. There are two options. Track 2 students take, in the fall term, a special one-term intensive course in general chemistry in place of the one-year course. In the second year, students study organic chemistry and take organic chemistry laboratory. Track 3 students take a one-year course in organic chemistry for first-year students and the one-term intensive general chemistry laboratory course. In the second year, students enroll in physical chemistry and the organic chemistry laboratory course. 

Additional information on the tracks can be found in the Requirements section.

Additional Courses

First-year students may also elect to take  CHEM UN2408. This seminar focuses on topics in modern chemistry, and is offered to all qualified students.

Biochemistry (BIOC UN3501, BIOC UN3512) is recommended for students interested in the biomedical sciences.

Physical chemistry (CHEM UN3079-CHEM UN3080), a one-year program, requires prior preparation in mathematics and physics. The accompanying laboratory is CHEM UN3085-CHEM UN3086.

Also offered are a senior seminar (CHEM UN3920); advanced courses in biochemistry, inorganic, organic, and physical chemistry; and an introduction to research (CHEM UN3098).

Sample Programs

Some typical programs are shown below. Programs are crafted by the student and the director of undergraduate studies to meet individual needs and interests.

Track 1

First Year
CHEM UN1403 General Chemistry I (Lecture)  
CHEM UN1404 General Chemistry II ( Lecture)  
CHEM UN1500 General Chemistry Laboratory  
CHEM UN2408 First-Year Seminar in Chemical Research  
Calculus and physics as required.  
Second Year
CHEM UN2443 Organic Chemistry I (Lecture)  
CHEM UN2444 Organic Chemistry II (Lecture)  
CHEM UN2493 Organic Chemistry Laboratory I (Techniques)  
CHEM UN2494 Organic Chemistry Laboratory II (Synthesis)  
Calculus and physics as required.  
Third Year
CHEM UN3079 Physical Chemistry I  
BIOC UN3501 Biochemistry: Structure and Metabolism  
CHEM UN3546 Advanced Organic Chemistry Laboratory  
CHEM UN3080 Physical Chemistry II  
CHEM UN3098 Supervised Independent Research  
Fourth Year
CHEM UN3085 Physical and Analytical Chemistry Laboratory I  
CHEM UN3086 Physical and Analytical Chemistry Laboratory II  
CHEM UN3920 Senior Seminar in Chemical Research  
CHEM GU4071 Inorganic Chemistry  
Advanced courses (4000-level or higher)  

Track 2

First Year
Calculus and physics as required.  
CHEM UN1507 Intensive General Chemistry Laboratory  
CHEM UN1604 Intensive General Chemistry (Lecture)  
CHEM UN2408 First-Year Seminar in Chemical Research  
Second Year
CHEM UN2443 Organic Chemistry I (Lecture)  
CHEM UN2444 Organic Chemistry II (Lecture)  
CHEM UN2493 Organic Chemistry Laboratory I (Techniques)  
CHEM UN2494 Organic Chemistry Laboratory II (Synthesis)  
Calculus and physics as required.  
Third Year
CHEM UN3079 Physical Chemistry I  
BIOC UN3501 Biochemistry: Structure and Metabolism  
CHEM UN3546 Advanced Organic Chemistry Laboratory  
CHEM UN3080 Physical Chemistry II  
CHEM UN3098 Supervised Independent Research  
Fourth Year
CHEM UN3085 Physical and Analytical Chemistry Laboratory I  
CHEM UN3086 Physical and Analytical Chemistry Laboratory II  
CHEM UN3920 Senior Seminar in Chemical Research  
CHEM GU4071 Inorganic Chemistry  
Advanced courses (4000- level or higher)  

Track 3

First Year
CHEM UN1507 Intensive General Chemistry Laboratory  
CHEM UN2045 Intensive Organic Chemistry I (Lecture)  
CHEM UN2046 Intensive Organic Chemistry II (Lecture)  
CHEM UN2408 First-Year Seminar in Chemical Research  
Calculus and Physics as required.  
Second Year
CHEM UN3079 Physical Chemistry I  
CHEM UN3080 Physical Chemistry II  
CHEM UN2545 Intensive Organic Chemistry Laboratory  
CHEM UN3546 Advanced Organic Chemistry Laboratory  
Calculus and physics as required.  
Third Year
BIOC UN3501 Biochemistry: Structure and Metabolism  
CHEM UN3085 Physical and Analytical Chemistry Laboratory I  
CHEM UN3086 Physical and Analytical Chemistry Laboratory II  
CHEM UN3098 Supervised Independent Research  
CHEM GU4071 Inorganic Chemistry  
Fourth Year
CHEM UN3920 Senior Seminar in Chemical Research  
Advanced courses (4000-level or higher)  

Professors

  • Bruce J. Berne
  • Ronald Breslow
  • Louis E. Brus
  • Virginia W. Cornish
  • Kenneth B. Eisenthal
  • Richard A. Friesner
  • Ruben Gonzalez
  • Laura Kaufman
  • James L. Leighton
  • Ann E. McDermott
  • Jack R. Norton
  • Colin Nuckolls
  • Gerard Parkin
  • David R. Reichman
  • Tomislav Rovis
  • Brent Stockwell
  • James J. Valentini
  • Xiaoyang Zhu

Associate Professors

  • Angelo Cacciuto
  • Luis Campos
  • Tristan Lambert
  • Wei Min
  • Jonathan Owen
  • Dalibor Sames
  • Latha Venkataraman

Assistant Professors

  • Xavier Roy

Senior Lecturer

Karen Phillips

Lecturers

  • Luis Avila
  • Robert Beer
  • John Decatur
  • Charles E. Doubleday
  • Sarah Hansen
  • Fay Ng
  • Ruben Savizky

Associates

  • Anna Ghurbanyan
  • Danielle Sedbrook
  • Joseph Ulichny

Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors

Students majoring in chemistry or in one of the interdepartmental majors in chemistry should go to the director of undergraduate studies or the undergraduate program manager in the Department of Chemistry to discuss their program of study. Chemistry majors and interdepartmental majors usually postpone part of the Core Curriculum beyond the sophomore year.

Chemistry Tracks

All students who wish to start with Track 2 or 3 courses must take a placement exam. The results of the placement exam are used to advise students which track to pursue. Unless otherwise specified below, all students must complete one of the following tracks:

Track 1

CHEM UN1403 General Chemistry I (Lecture)
CHEM UN1404 General Chemistry II ( Lecture)
CHEM UN1500 General Chemistry Laboratory
CHEM UN2443 Organic Chemistry I (Lecture)
CHEM UN2444 Organic Chemistry II (Lecture)
CHEM UN2493 Organic Chemistry Laboratory I (Techniques)
CHEM UN2494 Organic Chemistry Laboratory II (Synthesis)

Track 2

CHEM UN1500 General Chemistry Laboratory
CHEM UN1604 Intensive General Chemistry (Lecture)
CHEM UN2443 Organic Chemistry I (Lecture)
CHEM UN2444 Organic Chemistry II (Lecture)
CHEM UN2493 Organic Chemistry Laboratory I (Techniques)
CHEM UN2494 Organic Chemistry Laboratory II (Synthesis)

Track 3

CHEM UN1507 Intensive General Chemistry Laboratory
CHEM UN2045 Intensive Organic Chemistry I (Lecture)
CHEM UN2046 Intensive Organic Chemistry II (Lecture)
CHEM UN2545 Intensive Organic Chemistry Laboratory

Physics Sequences

The requirements for the physics sequences were modified on December 5, 2014. Students who declared before this date should contact the director of undergraduate studies for the department in order to confirm their correct course of study.

Unless otherwise specified below, all students must complete one of the following sequences:

Sequence A

For students with limited background in high school physics:

PHYS UN1401 Introduction To Mechanics and Thermodynamics
PHYS UN1402 Introduction To Electricity, Magnetism, and Optics
PHYS UN1403 Introduction to Classical and Quantum Waves
For chemistry majors, the following laboratory courses are recommended, NOT required. For chemical physics majors, the following laboratory courses are required:
PHYS UN1493 Introduction to Experimental Physics
PHYS UN2699 Experiments in Classical and Modern Physics
PHYS UN3081 Intermediate Laboratory Work

Sequence B

PHYS UN1601 Physics, I: Mechanics and Relativity
PHYS UN1602 Physics, II: Thermodynamics, Electricity, and Magnetism
PHYS UN2601 Physics, III: Classical and Quantum Waves
or PHYS UN3081 Intermediate Laboratory Work
For chemistry majors, the following laboratory courses are recommended NOT required. For chemical physics majors, the following laboratory courses are required:
PHYS UN2699 Experiments in Classical and Modern Physics

Sequence C

For students with advanced preparation in physics and mathematics:

PHYS UN2801
 - PHYS UN2802
Accelerated Physics I
and Accelerated Physics II
For chemistry majors, the following laboratory courses are recommended NOT required. For chemical physics majors, the following laboratory courses are required:
PHYS UN2699 Experiments in Classical and Modern Physics
or PHYS UN3081 Intermediate Laboratory Work

Major in Chemistry

Select one of the tracks outlined above in Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors and complete the following lectures and labs.

Chemistry
Select one of the chemistry tracks outlined above.
CHEM UN2408 First-Year Seminar in Chemical Research (Recommended NOT required)
CHEM UN3079 Physical Chemistry I
CHEM UN3080 Physical Chemistry II
CHEM UN3085 Physical and Analytical Chemistry Laboratory I
CHEM UN3086 Physical and Analytical Chemistry Laboratory II
CHEM UN3546 Advanced Organic Chemistry Laboratory
CHEM UN3920 Senior Seminar in Chemical Research
CHEM GU4071 Inorganic Chemistry
Select one course from the following:
CHEM UN3098 Supervised Independent Research
OR Chemistry courses numbered CHEM G4000 or above
Physics
Select one of the physics sequences outlined above in the Guidelines section.
Mathematics
Select one of the following sequences:
Four semesters of calculus:
MATH UN1101
 - MATH UN1102
 - MATH UN1201
 - MATH UN1202
Calculus I
and Calculus II
and Calculus III
and Calculus IV
Two semesters of honors mathematics:
MATH UN1207
 - MATH UN1208
Honors Mathematics A
and Honors Mathematics B

Major in Biochemistry

Select one of the tracks outlined above in Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors and complete the following lectures and labs.

Chemistry
Select one of the chemistry tracks outlined above.
CHEM UN2408 First-Year Seminar in Chemical Research (Recommended NOT required)
CHEM UN3079 Physical Chemistry I
CHEM UN3080 Physical Chemistry II
Biology
BIOL UN1908 First-Year Seminar in Modern Biology (Recommended NOT required)
BIOL UN2005 Introductory Biology I: Biochemistry, Genetics Molecular Biology
BIOL UN2006 Introductory Biology II: Cell Biology, Development Physiology
BIOC UN3501 Biochemistry: Structure and Metabolism
BIOC UN3512 Molecular Biology
Select one of the following laboratory courses:
BIOL UN3050 Project Laboratory In Protein Biochemistry
BIOL UN3052 Project Laboratory in Molecular Genetics
BIOL UN3500 Independent Biological Research
Physics
Select one of the following physics sequences:
Sequence A:
General Physics I
and General Physics II
Sequence B:
PHYS UN1401
 - PHYS UN1402
 - PHYS UN1403
Introduction To Mechanics and Thermodynamics
and Introduction To Electricity, Magnetism, and Optics
and Introduction to Classical and Quantum Waves (PHYS UN1403 is recommended NOT required)
Sequence C:
Physics, I: Mechanics and Relativity
and Physics, II: Thermodynamics, Electricity, and Magnetism
and Physics, III: Classical and Quantum Waves (PHYS UN2601 is recommended but not required)
Sequence D:
Accelerated Physics I
and Accelerated Physics II
Mathematics
Select one of the following sequences:
Two semesters of calculus:
MATH UN1101
 - MATH UN1102
 - MATH UN1201
 - MATH UN1202
Calculus I
and Calculus II
and Calculus III
and Calculus IV
Two semesters of honors mathematics:
MATH UN1207
 - MATH UN1208
Honors Mathematics A
and Honors Mathematics B
AP credit and one term of calculus (Calculus II or higher)
Additional Courses
Select one of the following additional laboratory courses:
BIOL UN3040
 - BIOL UN2501
Lab in Molecular Biology
and Contemporary Biology Laboratory
Project Laboratory In Protein Biochemistry
Project Laboratory in Molecular Genetics
Independent Biological Research
Physical and Analytical Chemistry Laboratory I
Physical and Analytical Chemistry Laboratory II
Supervised Independent Research
Advanced Organic Chemistry Laboratory
Select any three courses from the following:
Inorganic Chemistry
Chemistry for the Brain
Advanced Organic Chemistry
BIOPHYSICAL CHEMISTRY I
Biophysical Chemistry II
Ordinary Differential Equations
Ordinary Differential Equations
One additional semester of calculus
One additional semester of honors math:
MATH UN1207 Honors Mathematics A
or MATH UN1208 Honors Mathematics B
Any biology course at the 3000/4000 level for 3 or more points. The following are recommended:
Neurobiology I: Cellular and Molecular Neurobiology
Neurobiology II: Development Systems
The Cellular Physiology of Disease
Developmental Biology
Biotechnology
Cell Biology
Cellular and Molecular Immunology
Molecular Biology of Disease
Drugs and Disease

Major in Chemical Physics

Select one of the tracks outlined above in Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors and complete the following lectures and labs.

Chemistry
Select one of the chemistry tracks outlined above.
CHEM UN3079 Physical Chemistry I
CHEM UN3080 Physical Chemistry II
CHEM UN3085 Physical and Analytical Chemistry Laboratory I
CHEM UN3086 Physical and Analytical Chemistry Laboratory II
CHEM UN3098 Supervised Independent Research
CHEM GU4221 Quantum Chemistry
or PHYS GU4021 Quantum Mechanics
Physics
Select one of the physics sequences outlined above in Guidelines for all Chemistry Majors, Concentrators and Interdepartmental Majors. For the chemical physics major, one lab MUST be completed for the sequence chosen.
Complete the following lectures:
PHYS UN3003 Mechanics
PHYS UN3007 Electricity and Magnetism
PHYS UN3008 Electromagnetic Waves and Optics
Mathematics
Select one of the following sequences:
Four semesters of calculus:
MATH UN1101
 - MATH UN1102
 - MATH UN1201
 - MATH UN1202
Calculus I
and Calculus II
and Calculus III
and Calculus IV
Two semesters of honors mathematics:
MATH UN1207
 - MATH UN1208
 - MATH UN3027
Honors Mathematics A
and Honors Mathematics B
and Ordinary Differential Equations
Two semesters of advanced calculus:
MATH UN1202
 - MATH UN3027
Calculus IV
and Ordinary Differential Equations

Major in Environmental Chemistry

The requirements for this program were modified on February 1, 2016. Students who declared this program before this date should contact the director of undergraduate studies for the department in order to confirm their correct course of study.

Select one of the tracks outlined above in Guidelines for all Chemistry Majors, Concentrators, and Interdepartmental Majors and complete the following lectures and labs. 

Chemistry
Select one of the chemistry tracks outlined above. A second semester of Organic Chemistry lecture is recommended NOT required.
CHEM UN3079 Physical Chemistry I
CHEM GU4071 Inorganic Chemistry
The following courses are recommended NOT required:
CHEM UN2408 First-Year Seminar in Chemical Research
CHEM UN3920 Senior Seminar in Chemical Research
Earth and Environmental Science
Select two of the following three courses:
EESC UN2100 Earth's Environmental Systems: The Climate System
EESC UN2200 Earth's Environmental Systems: The Solid Earth System
EESC UN2300 Earth's Environmental Systems: The Life System
Additional course required:
EESC UN3101 Geochemistry for a Habitable Planet
Select one of the following labs:
EESC BC3016 Environmental Measurements
CHEM UN3085 Physical and Analytical Chemistry Laboratory I
Select one option for Independent Research in Environmental Chemistry:
EESC BC3800
 - EESC BC3801
Senior Research Seminar
and Senior Research Seminar
CHEM UN3098 Supervised Independent Research (It is strongly recommended to take CHEM UN3920 if taking CHEM UN3098)
Physics
Select one of the following physics sequences:
Sequence A:
PHYS UN1201
 - PHYS UN1202
General Physics I
and General Physics II
Sequence B:
PHYS UN1401
 - PHYS UN1402
 - PHYS UN1403
Introduction To Mechanics and Thermodynamics
and Introduction To Electricity, Magnetism, and Optics
and Introduction to Classical and Quantum Waves (Recommended NOT required)
Sequence C:
PHYS UN1601
 - PHYS UN1602
 - PHYS UN2601
Physics, I: Mechanics and Relativity
and Physics, II: Thermodynamics, Electricity, and Magnetism
and Physics, III: Classical and Quantum Waves (Recommended, not required)
Sequence D:
PHYS UN2801
 - PHYS UN2802
Accelerated Physics I
and Accelerated Physics II
Mathematics
Two semesters of calculus:
MATH UN1101 Calculus I
MATH UN1102 Calculus II
MATH UN1201 Calculus III
MATH UN1202 Calculus IV
Additional Courses
Select any two of the following:
Chemistry:
Physical Chemistry II
Organometallic Chemistry
Advanced Organic Chemistry
Earth and Environmental Science:
Environmental Data Analysis
Hydrology
Introduction to Atmospheric Science
Chemical Geology
Climate Thermodynamics and Energy Transfer
Global Assessment and Monitoring Using Remote Sensing
Earth Resources and Sustainable Development
Wetlands and Climate Change
The Chemistry of Continental Waters
Isoptope Geology II
Introduction to Atmospheric Chemistry
Principles of Physical Oceanography
Principles of Chemical Oceanography
Earth and Environmental Engineering:
Industrial ecology of earth resources
Introduction to aquatic chemistry
Mathematics:
One additonal semester of calculus

Concentration in Chemistry

No more than four points of CHEM UN3098 Supervised Independent Research may be counted toward the concentration.

Select one of the three chemistry tracks listed below.
PHYS UN1201
 - PHYS UN1202
General Physics I
and General Physics II
Two semesters of calculus

Chemistry Tracks

Track 1

CHEM UN1403 General Chemistry I (Lecture)
CHEM UN1404 General Chemistry II ( Lecture)
CHEM UN1500 General Chemistry Laboratory
Select 22 points of chemistry at the 2000-level or higher (excluding W2408).

Track 2

CHEM UN1500 General Chemistry Laboratory
or CHEM UN1507 Intensive General Chemistry Laboratory
CHEM UN1604 Intensive General Chemistry (Lecture)
Select 22 points of chemistry at the 2000-level or higher (excluding W2408).

Track 3

CHEM UN1507 Intensive General Chemistry Laboratory
CHEM UN2045 Intensive Organic Chemistry I (Lecture)
CHEM UN2046 Intensive Organic Chemistry II (Lecture)
Select 18 points of chemistry at the 2000-level or higher (excluding W2408).

Fall 2017

CHEM UN0001 Preparation for College Chemistry. 0 points.

Not for credit toward the bachelor's degree. Given on a Pass/Fail basis only.

Prerequisites: High school algebra or the instructor's permission. Recommended preparation: high school physics and chemistry.

This course is preparation for Chemistry UN1403 or the equivalent, as well as for other science courses. It is intended for students who have not attended school for sometime or who do not have a firm grasp of high school chemistry. Topics include inorganic nomenclature, chemical reactions, chemical bonding and its relation to molecular structure, stoichiometry, periodic properties of elements, chemical equilibrium, gas laws, acids and bases, and electrochemistry.

Fall 2017: CHEM UN0001
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 0001 001/76539 T Th 6:10pm - 7:25pm
Room TBA
Luis Avila 0 2/50

CHEM UN1403 General Chemistry I (Lecture). 4 points.

CC/GS: Partial Fulfillment of Science Requirement

Corequisites: MATH UN1101

Preparation equivalent to one year of high school chemistry is assumed. Students lacking such preparation should plan independent study of chemistry over the summer or take CHEM UN0001 before taking CHEM UN1403. Topics include stoichiometry, states of matter, nuclear properties, electronic structures of atoms, periodic properties, chemical bonding, molecular geometry, introduction to quantum mechanics and atomic theory, introduction to organic and biological chemistry, solid state and materials science, polymer science and macromolecular structures and coordination chemistry. Although CHEM UN1403 and CHEM UN1404 are separate courses, students are expected to take both terms sequentially. The order of presentation of topics may differ from the order presented here, and from year to year. Students must ensure they register for the recitation that corresponds to the lecture section. Please check the Directory of Classes for details.

Spring 2017: CHEM UN1403
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1403 001/60068 M W 6:10pm - 7:25pm
417 International Affairs Bldg
Ruben Savizky 4 124/132
Fall 2017: CHEM UN1403
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1403 001/70912 M W 10:10am - 11:25am
Room TBA
Gerard Parkin 4 35/220
CHEM 1403 002/66037 T Th 10:10am - 11:25am
Room TBA
Ann McDermott 4 23/190
CHEM 1403 003/70633 T Th 6:10pm - 7:25pm
Room TBA
Ruben Savizky 4 17/190
CHEM 1403 004/77113 M W 6:10pm - 7:25pm
Room TBA
Robert Beer 4 12/132

CHEM UN1500 General Chemistry Laboratory. 3 points.

CC/GS: Partial Fulfillment of Science Requirement
Lab Fee: $140.

Corequisites: CHEM UN1403,CHEM UN1404

An introduction to basic techniques of modern experimental chemistry, including quantitative procedures and chemical analysis. Students must register for a Lab Lecture section for this course (CHEM UN1501). Please check the Directory of Classes for details. Please note that CHEM UN1500 is offered in the fall and spring semesters.

Spring 2017: CHEM UN1500
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1500 001/11815 M 1:10pm - 4:50pm
302c Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 20/24
CHEM 1500 002/77730 T 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 003/24530 T 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 004/77601 W 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 52/46
CHEM 1500 005/13047 W 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 32/46
CHEM 1500 006/12575 Th 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 007/62812 Th 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 36/46
CHEM 1500 008/72205 F 1:10pm - 4:50pm
302c Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 21/24
Fall 2017: CHEM UN1500
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1500 001/17071 T 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 12/46
CHEM 1500 002/60101 T 6:10pm - 9:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 23/46
CHEM 1500 003/70350 W 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 16/46
CHEM 1500 004/10677 Th 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 7/46

CHEM UN1507 Intensive General Chemistry Laboratory. 3 points.

CC/GS: Partial Fulfillment of Science Requirement
Lab Fee: $140.

Corequisites: CHEM UN2045

A student-centered experimental course intended for students who are taking or have completed CHEM UN1604 (Second Semester General Chemistry Intensive Lecture offered in Fall), CHEM UN2045 (Intensive Organic Chemistry offered in Fall), or CHEM UN2046 (Intensive Organic Chemistry Lecture offered in Spring). The course will provide an introduction to theory and practice of modern experimental chemistry in a contextual, student-centered collaborative learning environment. This course differs from CHEM UN1500 in its pedagogy and its emphasis on instrumentation and methods. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details. Please note that CHEM UN1507 is offered in the fall and spring semesters.

Spring 2017: CHEM UN1507
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1507 001/14709 F 1:00pm - 6:00pm
302 Havemeyer Hall
Luis Avila 3 15/18
CHEM 1507 002/65664 M 1:00pm - 6:00pm
302 Havemeyer Hall
Luis Avila 3 9/18
Fall 2017: CHEM UN1507
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1507 001/62266 F 1:00pm - 6:00pm
Room TBA
Luis Avila 3 2/18
CHEM 1507 002/22214 M 1:00pm - 6:00pm
Room TBA
Luis Avila 3 2/18

CHEM UN1604 Intensive General Chemistry (Lecture). 4 points.

CC/GS: Partial Fulfillment of Science Requirement

Prerequisites: A grade of "B" or better in CHEM UN1403 OR acceptable performance on the Department placement exam.
Corequisites: MATH UN1102

Topics include: gases (kinetic theory of gases); binary collision model for chemical reactions; chemical kinetics; acid-base equilibria; thermochemistry (thermodynamics I); spontaneous processes (thermodymanics II); chemical bonding in polyatomic molecules.  Students must ensure they register for the recitation that corresponds to the lecture section. Please check the Directory of Classes for details.

Fall 2017: CHEM UN1604
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1604 001/60955 M W 2:40pm - 3:55pm
Room TBA
Wei Min 4 2/120

CHEM UN2045 Intensive Organic Chemistry I (Lecture). 4 points.

Prerequisites: A grade of 5 on the Chemistry Advanced Placement exam and an acceptable grade on the Department placement exam or an acceptable grade in CHEM UN1604.
Corequisites: CHEM UN1507

Premedical students may take CHEM UN2045, CHEM UN2046, CHEM UN1507 and CHEM UN2545 to meet the minimum requirements for admission to medical school. This course covers the same material as CHEM UN2443-CHEM UN2444, but is intended for students who have learned the principles of general chemistry in high school OR have completed CHEM UN1604 in their first year at Columbia. First year students enrolled in CHEM UN2045-CHEM UN2046 are expected to enroll concurrently in CHEM UN1507. Although CHEM UN2045 and CHEM UN2046 are separate courses, students are expected to take both terms sequentially. A recitation section is required. Please check the Directory of Classes for details and also speak with the TA for the course.

Fall 2017: CHEM UN2045
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2045 001/10978 T Th 2:40pm - 3:55pm
Room TBA
Luis Campos 4 2/60

CHEM UN2443 Organic Chemistry I (Lecture). 4 points.

The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM UN2443 and CHEM UN2444 are separate courses, students are expected to take both terms sequentially.  Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details.

Fall 2017: CHEM UN2443
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2443 001/27305 M W 1:10pm - 2:25pm
Room TBA
Tristan Lambert 4 150/150
CHEM 2443 002/24084 T Th 11:40am - 12:55pm
Room TBA
Karen Phillips 4 61/190
CHEM 2443 003/71397 M W 6:10pm - 7:25pm
Room TBA
Charles Doubleday 4 131/132

CHEM UN2493 Organic Chemistry Laboratory I (Techniques). 1.5 point.

Lab Fee: $63.00

Corequisites: CHEM UN2443

Techniques of experimental organic chemistry, with emphasis on understanding fundamental principles underlying the experiments in methodology of solving laboratory problems involving organic molecules. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM UN2493 is the first part of a full year organic chemistry laboratory course. Students must register for the lab lecture section (CHEM UN2495) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisors for further information.

Fall 2017: CHEM UN2493
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2493 001/19092 M 1:10pm - 5:00pm
Room TBA
Danielle Sedbrook 1.5 24/24
CHEM 2493 002/26653 T 1:10pm - 5:00pm
Room TBA
Danielle Sedbrook 1.5 24/24
CHEM 2493 003/61109 T 6:10pm - 9:50pm
Room TBA
Danielle Sedbrook 1.5 34/34
CHEM 2493 004/63980 W 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 23/34
CHEM 2493 005/66787 Th 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 28/34
CHEM 2493 006/72637 F 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 34/34
CHEM 2493 007/71082 M 1:10pm - 5:00pm
Room TBA
Danielle Sedbrook 1.5 17/24
CHEM 2493 008/29197 T 1:10pm - 5:00pm
Room TBA
Danielle Sedbrook 1.5 24/24
CHEM 2493 009/73928 T 6:10pm - 10:00pm
Room TBA
Danielle Sedbrook 1.5 34/34
CHEM 2493 010/16876 W 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 3/34
CHEM 2493 011/68246 Th 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 9/34
CHEM 2493 012/76039 F 1:10pm - 5:00pm
Room TBA
Anna Ghurbanyan 1.5 34/34

CHEM UN2545 Intensive Organic Chemistry Laboratory. 3 points.

Lab Fee: $125.

The course covers the same material as CHEM UN2493-CHEM UN2494, but is intended for those students who have taken Intensive Organic Chemistry, CHEM UN2045-CHEM UN2046, and for students who intend to major in Chemistry, Biochemistry, Chemical Physics, or Environmental Chemistry.

Fall 2017: CHEM UN2545
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2545 001/10182 M 1:10pm - 6:00pm
Room TBA
Fay Ng 3 9/10
CHEM 2545 002/64960 T 1:10pm - 6:00pm
Room TBA
Fay Ng 3 9/10

CHEM UN3079 Physical Chemistry I. 4 points.

Prerequisites: PHYS UN1201-UN1202 is acceptable; PHYS UN1401-UN1402 or the equivalent is HIGHLY recommended.
Corequisites: CHEM UN3085

Elementary, but comprehensive, treatment of the fundamental laws governing the behavior of individual atoms and molecules and collections of them. CHEM UN3079 covers the thermodynamics of chemical systems at equilibrium and the chemical kinetics of nonequilibrium systems. Although CHEM UN3079 and CHEM UN3080 are separate courses, students are expected to take both terms sequentially. A recitation section is required.  Please check the Directory of Classes for details and also speak with the TA for the course.

Fall 2017: CHEM UN3079
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3079 001/75179 M W 11:40am - 12:55pm
Room TBA
Laura Kaufman 4 34/60

CHEM UN3085 Physical and Analytical Chemistry Laboratory I. 4 points.

Lab Fee: $125 per term.

Corequisites: CHEM UN3079

A student-centered experimental course intended for students who are co-registered or have completed CHEM UN3079 and CHEM UN3080. The course emphasizes techniques of experimental physical chemistry and instrumental analysis, including vibrational, electronic, and laser spectroscopy; electroanalytical methods; calorimetry; reaction kinetics; hydrodynamic methods; scanning probe microscopy; applications of computers to reduce experimental data; and computational chemistry. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details.

Fall 2017: CHEM UN3085
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3085 001/61909 T 12:00pm - 6:00pm
Room TBA
Luis Avila 4 9/15

CHEM UN3098 Supervised Independent Research. 4 points.

Lab Fee: $105 per term.

Prerequisites: the instructor's permission for entrance, and the departmental representative's permission for aggregate points in excess of 12 or less than 4.

This course may be repeated for credit (see major and concentration requirements). Individual research under the supervision of a member of the staff. Research areas include organic, physical, inorganic, analytical, and biological chemistry. Please note that CHEM UN3098 is offered in the fall and spring semesters.

Spring 2017: CHEM UN3098
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3098 001/10986  
Vesna Gasperov 4 8/25
Fall 2017: CHEM UN3098
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3098 001/71650  
Vesna Gasperov 4 6/25

CHEM UN3920 Senior Seminar in Chemical Research. 2 points.

Pass/Fail credit only.

Open to senior chemistry, biochemistry, environmental chemistry, and chemical physics majors; senior chemistry concentrators; and students who have taken or are currently enrolled in CHEM UN3098. Senior seminar provides direct access to modern chemical research through selected studies by the students from active fields of chemical research. Topics to be presented and discussed draw from the current scientific literature and/or UN3098 research.

Fall 2017: CHEM UN3920
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3920 001/15656 F 2:10pm - 4:00pm
Room TBA
Karen Phillips 2 6/40

BIOC UN3300 Biochemistry. 3 points.

Prerequisites: one year each of Introductory Biology and General Chemistry.
Corequisites: Organic Chemistry. Primarily aimed at nontraditional students and undergraduates who have course conflicts with BIOC C3501.

Biochemistry is the study of the chemical processes within organisms that give rise to the immense complexity of life. This complexity emerges from a highly regulated and coordinated flow of chemical energy from one biomolecule to another. This course serves to familiarize students with the spectrum of biomolecules (carbohydrates, lipids, amino acids, nucleic acids, etc.) as well as the fundamental chemical processes (glycolysis, citric acid cycle, fatty acid metabolism, etc.) that allow life to happen. In particular, this course will employ active learning techniques and critical thinking problem-solving to engage students in answering the question: how is the complexity of life possible? NOTE: While Organic Chemistry is listed as a corequisite, it is highly recommended that you take Organic Chemistry beforehand.

Spring 2017: BIOC UN3300
Course Number Section/Call Number Times/Location Instructor Points Enrollment
BIOC 3300 001/21782 T 7:10pm - 9:30pm
329 Pupin Laboratories
Danny Ho 3 79/85
Fall 2017: BIOC UN3300
Course Number Section/Call Number Times/Location Instructor Points Enrollment
BIOC 3300 001/23729 T 7:10pm - 9:30pm
Room TBA
Danny Ho 3 65/65

BIOC UN3501 Biochemistry: Structure and Metabolism. 4 points.

Discussion Section Required

Prerequisites: one year of BIOL C2005 and BIOL C2006 and one year of organic chemistry.

Lecture and recitation. Students wishing to cover the full range of modern biochemistry should take both BIOC C3501 and C3512. C3501 covers subject matters in modern biochemistry, including chemical biology and structural biology, discussing the structure and function of both proteins and small molecules in biological systems. Proteins are the primary class of biological macromolecules and serve to carry out most cellular functions. Small organic molecules function in energy production and creating building blocks for the components of cells and can also be used to perturb the functions of proteins directly. The first half of the course covers protein structure, enzyme kinetics and enzyme mechanism. The second half of the course explores how small molecules are used endogenously by living systems in metabolic and catabolic pathways; this part of the course focuses on mechanistic organic chemistry involved in metabolic pathways.

Fall 2017: BIOC UN3501
Course Number Section/Call Number Times/Location Instructor Points Enrollment
BIOC 3501 001/19218 T Th 2:40pm - 3:55pm
Room TBA
4 128/180

CHEM GU4071 Inorganic Chemistry. 4.5 points.

Prerequisites: CHEM W3443-CHEM W3444 or CHEM W3045-CHEM W3046.

Principles governing the structure and reactivity of inorganic compounds surveyed from experimental and theoretical viewpoints.  Topics include inorganic solids, aqueous and nonaqueous solutions, the chemistry of selected main group elements, transition metal chemistry, metal clusters, metal carbonyls, and organometallic chemistry.

Fall 2017: CHEM GU4071
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4071 001/17834 M W 8:40am - 9:55am
Room TBA
Jonathan Owen 4.5 18/42

CHEM GU4147 Advanced Organic Chemistry. 4.5 points.

Prerequisites: elementary organic and physical chemistry.

The mechanisms of organic reactions, structure of organic molecules, and theories of reactivity. How reactive intermediates are recognized and mechanisms are deduced using kinetics, stereochemistry, isotopes, and physical measurements.

Fall 2017: CHEM GU4147
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4147 001/75049 T Th 10:10am - 11:25am
Room TBA
Dalibor Sames, Jack Norton 4.5 4/42

CHEM GU4148 Synthetic Methods in Organic Chemistry I. 4.5 points.

This course is intended for graduate students and advanced undergraduate students. The main purpose of the course is to introduce students to modern synthetic chemistry via the selected series of topics (synthetic planning and the logic of organic assembly, classical and new reactions/methods and their use in complex target synthesis). Mechanistic underpinning of the discussed reaction processes will also be briefly discussed. For each module (see the content below), specific examples of syntheses of natural products and/or synthetic materials will be provided. In addition to lectures by Prof. Sames, students will select and present relevant papers in the class (the number of student symposia will depend on the final enrollment in this course). The basic knowledge of transition metal chemistry is recommended for the cross-coupling reactions (i.e., structure, electron counting, and elemental reaction types of transition metals).

Fall 2017: CHEM GU4148
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4148 001/17337 M W 10:10am - 11:25am
Room TBA
Tristan Lambert, Tomislav Rovis 4.5 5/42

CHEM GU4221 Quantum Chemistry. 4.5 points.

Prerequisites: elementary physical chemistry.

Basic quantum mechanics: the Schrodinger equation and its interpretation, exact solutions in simple cases, methods or approximation, angular Mementum and electronic spin, and an introduction to atomic and molecular structure.

Fall 2017: CHEM GU4221
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4221 001/24026 M W 11:40am - 12:55pm
Room TBA
Richard Friesner 4.5 3/42

CHEM GU4230 Statistical Mechanics. 4.5 points.

Prerequisites: elementary physical chemistry.
Corequisites: CHEM G4221.

Topics include the classical and quantum statistical mechanics of gases, liquids, and solids.

Fall 2017: CHEM GU4230
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4230 001/63159 M W 1:10pm - 2:25pm
Room TBA
Bruce Berne 4.5 1/42

CHEM GU4312 Chemical Biology. 4 points.

Development and application of chemical methods for understanding the molecular mechanisms of cellular processes. Review of the biosynthesis, chemical synthesis, and structure and function of proteins and nucleic acids. Application of chemical methods--including structural biology, enzymology, chemical genetics, and the synthesis of modified biological molecules--to the study of cellular processes--including transcription, translation, and signal transduction.

Spring 2017

CHEM UN1403 General Chemistry I (Lecture). 4 points.

CC/GS: Partial Fulfillment of Science Requirement

Corequisites: MATH UN1101

Preparation equivalent to one year of high school chemistry is assumed. Students lacking such preparation should plan independent study of chemistry over the summer or take CHEM UN0001 before taking CHEM UN1403. Topics include stoichiometry, states of matter, nuclear properties, electronic structures of atoms, periodic properties, chemical bonding, molecular geometry, introduction to quantum mechanics and atomic theory, introduction to organic and biological chemistry, solid state and materials science, polymer science and macromolecular structures and coordination chemistry. Although CHEM UN1403 and CHEM UN1404 are separate courses, students are expected to take both terms sequentially. The order of presentation of topics may differ from the order presented here, and from year to year. Students must ensure they register for the recitation that corresponds to the lecture section. Please check the Directory of Classes for details.

Spring 2017: CHEM UN1403
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1403 001/60068 M W 6:10pm - 7:25pm
417 International Affairs Bldg
Ruben Savizky 4 124/132
Fall 2017: CHEM UN1403
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1403 001/70912 M W 10:10am - 11:25am
Room TBA
Gerard Parkin 4 35/220
CHEM 1403 002/66037 T Th 10:10am - 11:25am
Room TBA
Ann McDermott 4 23/190
CHEM 1403 003/70633 T Th 6:10pm - 7:25pm
Room TBA
Ruben Savizky 4 17/190
CHEM 1403 004/77113 M W 6:10pm - 7:25pm
Room TBA
Robert Beer 4 12/132

CHEM UN1404 General Chemistry II ( Lecture). 4 points.

CC/GS: Partial Fulfillment of Science Requirement

Although CHEM UN1403 and CHEM UN1404 are separate courses, students are expected to take both terms sequentially. Topics include gases, kinetic theory of gases, states of matter: liquids and solids, chemical equilibria, applications of equilibria, acids and bases, chemical thermodynamics, energy, enthalpy, entropy, free energy, periodic properties, chemical kinetics, and electrochemistry. The order of presentation of topics may differ from the order presented here, and from year to year.  Students must ensure they register for the recitation that corresponds to the lecture section. Please check the Directory of Classes for details.

Spring 2017: CHEM UN1404
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1404 001/72995 M W 8:40am - 9:55am
309 Havemeyer Hall
Angelo Cacciuto 4 179/190
CHEM 1404 002/60993 M W 10:10am - 11:25am
309 Havemeyer Hall
Wei Min 4 104/190
CHEM 1404 003/77372 M W 6:10pm - 7:25pm
301 Pupin Laboratories
Robert Beer 4 140/162

CHEM UN1500 General Chemistry Laboratory. 3 points.

CC/GS: Partial Fulfillment of Science Requirement
Lab Fee: $140.

Corequisites: CHEM UN1403,CHEM UN1404

An introduction to basic techniques of modern experimental chemistry, including quantitative procedures and chemical analysis. Students must register for a Lab Lecture section for this course (CHEM UN1501). Please check the Directory of Classes for details. Please note that CHEM UN1500 is offered in the fall and spring semesters.

Spring 2017: CHEM UN1500
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1500 001/11815 M 1:10pm - 4:50pm
302c Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 20/24
CHEM 1500 002/77730 T 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 003/24530 T 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 004/77601 W 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 52/46
CHEM 1500 005/13047 W 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 32/46
CHEM 1500 006/12575 Th 1:10pm - 4:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 44/46
CHEM 1500 007/62812 Th 6:10pm - 9:50pm
302 Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 36/46
CHEM 1500 008/72205 F 1:10pm - 4:50pm
302c Havemeyer Hall
Joseph Ulichny, Sarah Hansen 3 21/24
Fall 2017: CHEM UN1500
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1500 001/17071 T 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 12/46
CHEM 1500 002/60101 T 6:10pm - 9:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 23/46
CHEM 1500 003/70350 W 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 16/46
CHEM 1500 004/10677 Th 1:10pm - 4:50pm
Room TBA
Joseph Ulichny, Sarah Hansen 3 7/46

CHEM UN1507 Intensive General Chemistry Laboratory. 3 points.

CC/GS: Partial Fulfillment of Science Requirement
Lab Fee: $140.

Corequisites: CHEM UN2045

A student-centered experimental course intended for students who are taking or have completed CHEM UN1604 (Second Semester General Chemistry Intensive Lecture offered in Fall), CHEM UN2045 (Intensive Organic Chemistry offered in Fall), or CHEM UN2046 (Intensive Organic Chemistry Lecture offered in Spring). The course will provide an introduction to theory and practice of modern experimental chemistry in a contextual, student-centered collaborative learning environment. This course differs from CHEM UN1500 in its pedagogy and its emphasis on instrumentation and methods. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details. Please note that CHEM UN1507 is offered in the fall and spring semesters.

Spring 2017: CHEM UN1507
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1507 001/14709 F 1:00pm - 6:00pm
302 Havemeyer Hall
Luis Avila 3 15/18
CHEM 1507 002/65664 M 1:00pm - 6:00pm
302 Havemeyer Hall
Luis Avila 3 9/18
Fall 2017: CHEM UN1507
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 1507 001/62266 F 1:00pm - 6:00pm
Room TBA
Luis Avila 3 2/18
CHEM 1507 002/22214 M 1:00pm - 6:00pm
Room TBA
Luis Avila 3 2/18

CHEM UN2046 Intensive Organic Chemistry II (Lecture). 4 points.

Premedical students may take CHEM W2045CHEM W2046, and CHEM W2545 to meet the minimum requirements for admission to medical school. This course covers the same material as CHEM W2443-CHEM  W2444, but is intended for students who have learned the principles of general chemistry in high school OR have completed CHEM W1604 in their first year at Columbia. First year students enrolled in CHEM W2045-CHEM W2046 are expected to enroll concurrently in CHEM W1507. Although CHEM W2045 and CHEM W2046 are separate courses, students are expected to take both terms sequentially. A recitation section is required.  Please check the Directory of Classes for details and also speak with the TA for the course.

Spring 2017: CHEM UN2046
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2046 001/70127 T Th 11:40am - 12:55pm
633 Seeley W. Mudd Building
Colin Nuckolls 4 26/60

CHEM UN2408 First-Year Seminar in Chemical Research. 1 point.

Prerequisites: CHEM W1403, CHEM W1604, CHEM W3045, or the instructor's permission.

A one-hour weekly lecture, discussion, and critical analysis of topics that reflect problems in modern chemistry, with emphasis on current areas of active chemical research.

Spring 2017: CHEM UN2408
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2408 001/61249 F 12:00pm - 12:50pm
209 Havemeyer Hall
Vesna Gasperov 1 31/80

CHEM UN2444 Organic Chemistry II (Lecture). 4 points.

The principles of organic chemistry. The structure and reactivity of organic molecules are examined from the standpoint of modern theories of chemistry. Topics include stereochemistry, reactions of organic molecules, mechanisms of organic reactions, syntheses and degradations of organic molecules, and spectroscopic techniques of structure determination. Although CHEM W2443 and CHEM W2444 are separate courses, students are expected to take both terms sequentially.  Students must ensure they register for the recitation which corresponds to the lecture section. Please check the Directory of Classes for details.

Spring 2017: CHEM UN2444
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 2444 001/75858 T Th 11:40am - 12:55pm
309 Havemeyer Hall
Karen Phillips 4 130/250
CHEM 2444 002/70006 M W 6:10pm - 7:25pm
309 Havemeyer Hall
Charles Doubleday 4 155/162

CHEM UN2494 Organic Chemistry Laboratory II (Synthesis). 1.5 point.

Lab Fee: $62.00

Prerequisites: CHEM W1403-CHEM W1404; CHEM W1500; CHEM W2493.
Corequisites: CHEM W2444.

Please note that you must complete CHEM W2493 before you register for CHEM W2494. This lab introduces students to experimental design and trains students in the execution and evaluation of scientific data. The technique experiments in the first half of the course (CHEM W2493) teach students to develop and master the required experimental skills to perform the challenging synthesis experiments in the second semester. The learning outcomes for this lab are the knowledge and experimental skills associated with the most important synthetic routes widely used in industrial and research environments. Attendance at the first lab lecture and laboratory session is mandatory. Please note that CHEM W2494 is the second part of a full year organic chemistry laboratory course. Students must register for the lab lecture section (CHEM W2496) which corresponds to their lab section. Students must attend ONE lab lecture and ONE lab section every other week. Please contact your advisors for further information.

CHEM UN3080 Physical Chemistry II. 4 points.

Prerequisites: CHEM W3079
Corequisites: CHEM W3086 is acceptable.

CHEM W3080 covers the quantum mechanics of atoms and molecules, the quantum statistical mechanics of chemical systems, and the connection of statistical mechanics to thermodynamics. Although CHEM W3079 and CHEM W3080 are separate courses, students are expected to take both terms sequentially. A recitation section is required.  Please check the Directory of Classes for details and also speak with the TA for the course.

Spring 2017: CHEM UN3080
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3080 001/27448 M W 11:40am - 12:55pm
209 Havemeyer Hall
Xiaoyang Zhu 4 32/60

CHEM UN3086 Physical and Analytical Chemistry Laboratory II. 4 points.

Lab Fee: $125 per term.

Prerequisites: CHEM W3085
Corequisites: CHEM W3080 for CHEM W3086 is acceptable.

A student-centered experimental course intended for students who are co-registered or have completed CHEM W3079 and CHEM W3080. The course emphasizes techniques of experimental physical chemistry and instrumental analysis, including vibrational, electronic, and laser spectroscopy; electroanalytical methods; calorimetry; reaction kinetics; hydrodynamic methods; scanning probe microscopy; applications of computers to reduce experimental data; and computational chemistry. Students must also attend the compulsory Mentoring Session. Please check the Directory of Classes for details.

Spring 2017: CHEM UN3086
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3086 001/73734 T 12:00pm - 6:00pm
222 Havemeyer Hall
Luis Avila 4 9/15

CHEM UN3098 Supervised Independent Research. 4 points.

Lab Fee: $105 per term.

Prerequisites: the instructor's permission for entrance, and the departmental representative's permission for aggregate points in excess of 12 or less than 4.

This course may be repeated for credit (see major and concentration requirements). Individual research under the supervision of a member of the staff. Research areas include organic, physical, inorganic, analytical, and biological chemistry. Please note that CHEM UN3098 is offered in the fall and spring semesters.

Spring 2017: CHEM UN3098
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3098 001/10986  
Vesna Gasperov 4 8/25
Fall 2017: CHEM UN3098
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3098 001/71650  
Vesna Gasperov 4 6/25

BIOC UN3512 Molecular Biology. 3 points.

Prerequisites: one year of biology. Recommended but not required: BIOC C3501.

This is a lecture course designed for advanced undergraduates and graduate students. The focus is on understanding at the molecular level how genetic information is stored within the cell and how it is regulated. Topics covered include genome organization, DNA replication, transcription, RNA processing, and translation. This course will also emphasize the critical analysis of the scientific literature and help students understand how to identify important biological problems and how to address them experimentally. SCE and TC students may register for this course, but they must first obtain the written permission of the instructor, by filling out a paper Registration Adjustment Form (Add/Drop form). The form can be downloaded at the URL below, but must be signed by the instructor and returned to the office of the registrar.  http://registrar.columbia.edu/sites/default/files/content/reg-adjustment.pdf

Spring 2017: BIOC UN3512
Course Number Section/Call Number Times/Location Instructor Points Enrollment
BIOC 3512 001/23721 M W 2:40pm - 3:55pm
614 Schermerhorn Hall
James Manley, Mauricio Arias Hernandez 3 40/101

CHEM UN3546 Advanced Organic Chemistry Laboratory. 3 points.

Laboratory Fee: $125.

Prerequisites: CHEM W3543 or CHEM W3545.
Corequisites: CHEM W3444 or CHEM W3444.

A project laboratory with emphasis on complex synthesis and advanced techniques including qualitative organic analysis and instrumentation.

Spring 2017: CHEM UN3546
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 3546 001/28566 M 1:00pm - 6:00pm
202b Havemeyer Hall
Fay Ng 3 8/10
CHEM 3546 002/16619 T 1:00pm - 6:00pm
202b Havemeyer Hall
Fay Ng 3 5/10

CHEM GU4102 Chemistry for the Brain. 4.5 points.

This course was upgraded from 2.5 to 4.5 and assigned a new number.

Prerequisites: organic chemistry and biology courses, neuroscience or neurobiology recommended, but not required.

The study of the brain is one of the most exciting frontiers in science and medicine today.  Although neuroscience is by nature a multi-disciplinary effort, chemistry has played many critical roles in the development of modern neuroscience, neuropharmacology, and brain imaging.  Chemistry, and the chemical probes it generates, such as molecular modulators, therapeutics, imaging agents, sensors, or actuators, will continue to impact neuroscience on both preclinical and clinical levels.  In this course, two major themes will be discussed.  In the first one, titled "Imaging brain function with chemical tools," we will discuss molecular designs and functional parameters of widely used fluorescent sensors in neuroscience (calcium, voltage, and neurotransmitter sensors), their impact on neuroscience, pros and cons of genetically encoded sensors versus chemical probes, and translatability of these approaches to the human brain.  In the second major theme, titled "Perturbation of the brain function with chemical tools," we will examine psychoactive substances, the basics of medicinal chemistry, brain receptor activation mechanisms and coupled signaling pathways, and their effects on circuit and brain function.  We will also discuss recent approaches, failures and successes in the treatment of neurodegenerative and psychiatric disorders.  Recent advances in precise brain function perturbation by light (optogenetics and photopharmacology) will also be introduced. In the context of both themes we will discuss the current and future possibilities for the design of novel materials, drawing on the wide molecular structural space (small molecules, proteins, polymers, nanomaterials), aimed at monitoring, modulating, and repairing human brain function.  This course is intended for students (undergraduate and graduate) from the science, engineering and medical departments.

Spring 2017: CHEM GU4102
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4102 001/16784 T Th 10:10am - 11:25am
320 Havemeyer Hall
Dalibor Sames 4.5 20/25

CHEM GU4145 NMR Spectroscopy. 1 point.

Prerequisites: elementary organic chemistry.

Introduction to theory and practice of NMR spectroscopy. Instrumental aspects, basic NMR theory, NOE, and a survey of 2D methods are covered.

Spring 2017: CHEM GU4145
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 4145 001/28629 F 11:00am - 11:50am
320 Havemeyer Hall
John Decatur 1 17/42

CHEM GU4210 Writing Workshop for Chemists. 1 point.

Prerequisites: recommended for undergraduate students to have taken at least one semester of independent research.

This course offers undergraduate and graduate students an introduction to scientific writing and provides an opportunity for them to become more familiar with the skill and craft of communicating complex scientific research. This course will provide students with the basic grammatical, stylistic and practical skills required to write effective academic journal articles, theses, or research proposals. In addition, through an innovative partnership with Columbia University Libraries' Digital Science Center, students will learn how to apply these basic skills to their writing through the use of state-of-the-art software and on-line resources. Regular opportunities to write, peer edit and revise throughout the semester will allow students to put what they are learning into immediate practice. It is recommended that undergraduates have taken at least one semester of research for credit before taking this course. Undergraduates should plan to take this course after taking the required Core course University Writing.

BIOC GU4324 Biophysical Chemistry II. 4 points.

This course provides a rigorous introduction to the theory underlying widely used biophysical methods, which will be illustrated by practical applications to contemporary biomedical research problems. The course has two equally important goals. The first goal is to explicate the fundamental approaches used by physical chemists to understand the behavior of molecules and to develop related analytical tools. The second goal is to prepare students to apply these methods themselves to their own research projects. The course will be divided into seven modules: (i) solution thermodynamics; (ii) hydrodynamic methods; (iii) statistical analysis of experimental data; (iv) basic quantum mechanics; (v) optical spectroscopy with an emphasis on fluorescence; (vi) nuclear magnetic resonance spectroscopy; and (vii) light-scattering and diffraction methods. In each module, the underlying physical theories and models with be presented and used to derive the mathematical equations applied to the analysis of experimental data. Weekly recitations will emphasize the analysis of real experimental data and understanding the applications of biophysical experimentation in published research papers.

Spring 2017: BIOC GU4324
Course Number Section/Call Number Times/Location Instructor Points Enrollment
BIOC 4324 001/23317 T F 4:10pm - 5:25pm
320 Havemeyer Hall
Ann McDermott, Ruben Gonzalez 4 7/100

Other Courses Offered in Alternating Years

Please contact the undergraduate program manager, Vesna Gasperov (vg2231@columbia.edu), for further information.

CHEM G4103 Organometallic Chemistry. 4.5 points.

Prerequisites: elementary organic chemistry. (Some background in inorganic and physical chemistry is helpful but not required.)

Main group and transition metal organometallic chemistry: bonding, structure, reactions, kinetics, and mechanisms.

CHEM G4232 Introduction to Molecular Modeling. 4.5 points.

Lab Required

Prerequisites: physical chemistry sequence.

Molecular modeling has become an integral part of research in many areas of chemistry, and in industry in drug discovery and materials design. Many experimental papers in the literature are routinely complemented by molecular modeling calculations. Experimental scientists working in industry have a significant advantage if they know how to optimally use modeling software. The course would consist of a normal lecture part plus a lab session every week in which the students learn to use modeling software by working on projects.

CHEM GR6168 Materials Chemistry IIA. 2.5 points.

Prerequisites: CHEM C3443 (or equivalent).

This is an introductory course to the emerging field macromolecular materials chemistry. The general topics will be based on the chemistry, self-assembly, and performance of block copolymers and conjugated polymers.  Particular emphasis will be devoted to the demands required to drive materials from scientific curiosity to commercialization.  At the fundamental level, the course will cover topics on polymerization techniques, electronic structure of organic semiconductors, characterization strategies, nanostructures and self-assembly.

CHEM G6169 Materials Chemistry IIB. 2.5 points.

Prerequisites: CHEM C3443 (or equivalent).

This is an introductory course to the field of inorganic nanomaterials chemistry. The course will cover the synthesis, the structural, electronic and magnetic characterization, and the physical properties of zero-, one- and two-dimensional inorganic nanomaterials. Particular emphasis will be devoted to the design of building blocks that can organize into functional assemblies and to the emergence of collective physical properties. The course will also explore the recent and developing electronic and optoelectronic applications of these materials.

CHEM GR6222 Quantum Chemistry II. 2.5 points.

Prerequisites: Quantum Chemistry G4221.

Atomic and molecular quantum mechanics: fundamentals of electronic structure, many-body wave functions and operators, Hartree-Fock and density functional theory, the Dirac equation.

Spring 2017: CHEM GR6222
Course Number Section/Call Number Times/Location Instructor Points Enrollment
CHEM 6222 001/27566 M W 11:40am - 12:55pm
320 Havemeyer Hall
Richard Friesner 2.5 8/42

CHEM G6231 Intermediate Statistical Mechanics. 2.5 points.

Prerequisites: CHEM G4221 and CHEM G4230.

Phase transitions and critical phenomena; renormalization group methods; classical theory of fluids.

CHEM GR8104 Structure Determination in Inorganic Chemistry. 2.5 points.

Not offered during 2017-18 academic year.

The determination of structures by diffraction methods, focusing on single crystal X-ray diffraction, is described. Emphasis is placed on a critical evaluation of published data.

CHEM GR8106 Kinetics. 2.5 points.

Not offered during 2017-18 academic year.

Kinetics and mechanisms of inorganic reactions.

CHEM G8111 Applications of NMR Spectroscopy to Inorganic Chemistry. 2.5 points.

The use of multinuclear NMR spectroscopy in the determination of the structures of inorganic molecules and the use of dynamic NMR spectroscopy (variable temperature NMR and magnetization transfer techniques) to provide information concerned with reaction mechanisms.

CHEM G8120 Polymers in Nanotechnology. 2.5 points.

Polymeric materials have long been ubiquitous items and played important roles in revolutionizing the way we live. Due to the advent of modern polymerization fabrication strategies, polymers are rapidly gaining interest for the development of next generation devices and medical treatment. This course will focus on the chemistry polymers and their use as nanostructured materials created by self-assembly and top-down fabrication techniques. Specifically, the class will be divided into two sections describing the uses of organic nanostructures on a) surfaces and b) as particles. Patterned surfaces will be described in terms of photo-, imprint-, and block copolymer lithography. The preparation of nanoparticles through polymer synthesis, dendrimers, and mechanical manipulation will be the second part.

CHEM G8130 The Chemistry of Nanocrystals. 2.5 points.

This course will provide a discussion of the thermodynamics and kinetics of colloidal crystallization and stabilization, the physical properties of quantum confined semiconductor and metal nanocrystals, methods of nanocrystal characterization, and examples of nanocrystals in technological applications.  Prospective students should be familiar with basic principles of quantum mechanics, thermodynamics of phase transitions, and inorganic chemistry – particularly molecular orbital theory.  Undergraduate students interested in this course should obtain approval from the instructor prior to registering.

CHEM G8232 Advanced Statistical Mechanics. 2.5 points.

Prerequisites: CHEM G4221 and CHEM G4230, or their equivalents.

Stochastic processes; Brownian motion; Langevin equations and fluctuation-dissipation theorems; reaction rate theory; time correlation functions and linear response theory.

CHEM GR8223 Quantum Chemistry, III. 2.5 points.

Not offered during 2017-18 academic year.

Prerequisites: CHEM G6222.

Nonlinear spectroscopy: second harmonic and vibrational sum frequency generation; applications to surface and colloidal nano-microparticle interfaces; nonradiative molecular processes.

CHEM G8349 Research Ethics & Philosophy. 2.5 points.

This lecture course aims to address philosophical and ethical questions in scientific research.  What are the most important traits of successful scientists whose discoveries have greatly benefited humanity (and led to Nobel Prizes)?  What distinguishes great science from mediocre or pathological "science"?  What are the ethical standards of scientific research?  How do we identify scientific misconduct or fraud?  Why are ethical standards so critical to the integrity of the research enterprise?  The course requires extensive participation of students in the form of discussions and debates.  Grades will be based on participation, writing assignments, and one oral presentation.